In the fall of 2011 the Sanofi Pasteur plant flooded causing problems with mold.  The facility, located in Toronto, Ontario, Canada, produced BCG vaccine products, made with the Glaxo 1077 strain,  such as a tuberculosis vaccine ImmuCYST, a BCG Immunotherapeutic -a bladder cancer drug. By April 2012 the FDA had found dozens of documented problems with sterility at the plant including mold, nesting birds and rusted electrical conduits.  The resulting closure of the plant for over two years resulting in shortages of bladder cancer and tuberculosis vaccines.  The Toronto Sanofi plant  On October 29, 2014 Health Canada gave the permission for Sanofi to resume production of BCG. 
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